Unique Telomere Probes For Targeted Testing
With the identification of a complete set of unique subtelomere probes, the hypothesis that telomeric imbalances contribute to a significant proportion of idiopathic mental retardation cases is now being more thoroughly examined.
Multiple strategies are being used to design whole genome telomere assays suitable for large population screening, including:
FISH - clinical testing now available
multi-color FISH (M-FISH)
spectral karyotyping (SKY)